The first inhabitants of the region were the Hittites and they called this area "Nissa". After the Hittites, the region was dominated by Phrygians and Lydians. In the 6th century, the Persians this region and BC. In the 4th century, the Macedonian King abolished the Persian (Iran) State and added Anatolia and Iran to the Macedonian Kingdom. After the death of the Macedonian King Alexander and the
collapse of the Macedonian Empire, this region was conquered by the Kingdom of Cappadocia. When the Roman Empire annexed the Cappadocia Kingdom, this region fell into the hands of the Roman Empire. After the division of the Roman Empire in 395, it fell into the share of Eastern Rome (Byzantium) like the other regions of Anatolia. In the 8th century, the Islamic armies conquered this region, which was in the triangle of "Niğde-Aksaray-Kayseri", and dominated it for 300 years. When the Islamic State was weakened by internal rebellion and separatist activities, the region was again captured by Byzantium. After the 1071 Malazgirt Victory, Anatolian Conqueror Kutalmışoğlu Süleyman Shah conquered this region like all Anatolia. The Turks called this village "Muşkara". After the collapse of the Seljuk State, in the middle of the 14th century, Ilkhanians were dominated by the Eratnaoğulları and Karamanoğulları. At the end of the fourteenth century, Nevşehir and its surrounding came under the rule of the Ottoman Empire. "Muşkara" village was a settlement of 10-12 houses. The Grand Vizier of the Tulip Period (1718-1730) Damad İbrahim Pasha of Nevşehir had the village of “Muşkara” built by expanding it. The newly established city was named "Nevşehir", which means "New city", and connected to Niğde Sanjak as an accident. While it was affiliated to Niğde during the Republic period, it became a province with the law numbered 6429 on 20.7.1954. Since then, it has been a charming province of our Central Anatolia region.